Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836851 | 0.86 | ALOX5 (0.42) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11830155 | 0.84 | PRKAG1 (0.44) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11836380 | 0.84 | PTGS1 (0.38) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11829271 | 0.83 | ADAMTS4 (0.38) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11826110 | 0.83 | HPGD (0.38) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11825726 | 0.83 | ALDH1A1 (0.38) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11831306 | 0.83 | AKR1C3 (0.56) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11829192 | 0.83 | HPGD (0.38) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11830219 | 0.83 | FFAR1 (0.39) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL11834196 | 0.83 | AKR1C3 (0.46) | AKR1C3AKR1C2LMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |