Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830955 | 0.92 | POLB (0.46) | POLBALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL11823392 | 0.89 | KMT2A (0.56) | POLBMAPTALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11819506 | 0.81 | KMT2A (0.56) | ALDH1A1SMN1; SMN2TSHRLMNATACR1 | |
| SCHEMBL11834769 | 0.80 | MEN1 (0.50) | POLBTSHRGAATACR1KMT2A | |
| SCHEMBL11830008 | 0.80 | PKM (0.48) | PKMPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL11822960 | 0.79 | TACR1 (0.69) | LMNATACR1KMT2AL3MBTL1 | |
| SCHEMBL11834886 | 0.79 | GFER (0.54) | POLBMAPTALDH1A1TSHRLMNA | |
| SCHEMBL11825601 | 0.78 | MAPT (0.64) | POLBMAPTALDH1A1HTTLMNA | |
| SCHEMBL11828042 | 0.77 | GFER (0.55) | MAPTLMNANPSR1TACR1KMT2A | |
| SCHEMBL11823642 | 0.74 | SLC2A1 (0.46) | POLBMAPTALDH1A1PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |