Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829997 | 0.92 | PKM (0.48) | POLBTACR1PTGDR2ALDH1A1TSHR | |
| SCHEMBL11834769 | 0.89 | MEN1 (0.50) | POLBSIGMAR1TACR1PTGDR2TSHR | |
| SCHEMBL11830966 | 0.81 | SIGMAR1 (0.44) | POLBACHESIGMAR1DRD2KCNJ1 | |
| SCHEMBL11823392 | 0.81 | KMT2A (0.56) | POLBTACR1PTGDR2ALDH1A1TSHR | |
| SCHEMBL11822960 | 0.78 | TACR1 (0.69) | TACR1KMT2AL3MBTL1 | |
| SCHEMBL11834886 | 0.78 | GFER (0.54) | POLBTACR1ALDH1A1TSHRKMT2A | |
| SCHEMBL11827870 | 0.77 | SIGMAR1 (0.58) | SIGMAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11828042 | 0.76 | GFER (0.55) | TACR1KMT2A | |
| SCHEMBL18919147 | 0.75 | MAPT (0.56) | ACHEALDH1A1KMT2ADRD2HTR2A | |
| SCHEMBL11825601 | 0.75 | MAPT (0.64) | POLBTACR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |