Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841997 | 0.88 | ADRA2A (0.70) | LMNAMEN1KMT2ADRD2DRD4 | |
| SCHEMBL11841817 | 0.81 | ADRA2A (0.60) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11840670 | 0.80 | SIRT1 (0.61) | LMNACYP2D6KMT2ADRD2DRD4 | |
| SCHEMBL11860457 | 0.80 | ADRA2A (0.59) | LMNAMEN1KMT2ADRD2DRD4 | |
| SCHEMBL11838568 | 0.80 | MAPT (0.65) | LMNAHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8681469 | 0.79 | SIGMAR1 (0.71) | LMNABCHECYP2D6HTTALDH1A1 | |
| SCHEMBL11848458 | 0.79 | CDK4 (0.59) | LMNADRD2DRD4DRD3ADRA2A | |
| SCHEMBL11848772 | 0.79 | TRPV1 (0.62) | DRD2DRD4DRD3ADRA2AADRA2B | |
| SCHEMBL7325154 | 0.78 | ADRA2A (0.68) | LMNABCHECYP2D6HTTALDH1A1 | |
| SCHEMBL11843398 | 0.78 | ADRA2A (0.56) | BCHEHTTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997539-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |