Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835254 | 0.87 | PPARG (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27915165 | 0.85 | TSHR (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11847061 | 0.85 | MMP8 (0.39) | ALDH1A1HIF1ATSHRMAPK1KDM4E | |
| SCHEMBL11846077 | 0.84 | MMP8 (0.41) | ALDH1A1HIF1ATSHRMAPK1KDM4E | |
| SCHEMBL11841890 | 0.84 | ALDH1A1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11837748 | 0.84 | MAPT (0.49) | ALDH1A1HPGDHIF1ATSHRMEN1 | |
| SCHEMBL11790207 | 0.84 | CASP1 (0.47) | ALDH1A1HPGDKDM4ECDC7DBF4 | |
| SCHEMBL11836694 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10HIF1AMAPK1 | |
| SCHEMBL11839726 | 0.83 | PPARG (0.47) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL11835794 | 0.83 | PTPRC (0.51) | ALDH1A1HPGDMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |