Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835254 | 0.85 | PPARG (0.46) | ALDH1A1MMP8PIN1SMN1; SMN2MEN1 | |
| SCHEMBL11836053 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MMP8HDAC3HDAC4 | |
| SCHEMBL11847061 | 0.84 | MMP8 (0.39) | ALDH1A1MMP8PIN1SMN1; SMN2MEN1 | |
| SCHEMBL11836617 | 0.84 | CA12 (0.42) | ALDH1A1HSD17B10MMP8PIN1SMN1; SMN2 | |
| SCHEMBL11845881 | 0.83 | LTA4H (0.42) | ALDH1A1HSD17B10SMN1; SMN2NPC1KMT2A | |
| SCHEMBL11790207 | 0.83 | CASP1 (0.47) | ALDH1A1MMP8SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11837748 | 0.83 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11846077 | 0.83 | MMP8 (0.41) | ALDH1A1MMP8PIN1SMN1; SMN2MEN1 | |
| SCHEMBL11839726 | 0.82 | PPARG (0.47) | ALDH1A1HSD17B10SMN1; SMN2MEN1NPC1 | |
| SCHEMBL11835794 | 0.82 | PTPRC (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |