Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836617 | 0.87 | CA12 (0.42) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL11847061 | 0.87 | MMP8 (0.39) | TDP1MMP8PIN1MEN1NPC1 | |
| SCHEMBL11790207 | 0.85 | CASP1 (0.47) | GRIA2GRIA4MMP8MEN1KMT2A | |
| SCHEMBL11846077 | 0.85 | MMP8 (0.41) | TDP1MMP8PIN1MEN1NPC1 | |
| SCHEMBL11836694 | 0.85 | ALDH1A1 (0.45) | TDP1MMP8PIN1MEN1NPC1 | |
| SCHEMBL11837748 | 0.85 | MAPT (0.49) | PPARGPPARAGRIA2GRIA4MEN1 | |
| SCHEMBL11839726 | 0.84 | PPARG (0.47) | PPARGPPARATDP1GRIA2GRIA4 | |
| SCHEMBL11835794 | 0.84 | PTPRC (0.51) | TDP1GRIA2GRIA4MEN1KMT2A | |
| SCHEMBL11833508 | 0.84 | PTGS2 (0.49) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL11837622 | 0.84 | PPARG (0.45) | PPARGPPARASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |