Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | BCL6 | P41182 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383012 | 0.98 | PKM (0.56) | PKMNPC1RAB9ANAMPTATG4B | |
| SCHEMBL525722 | 0.83 | ALDH1A1 (0.57) | PKMNPC1RAB9ANAMPTATG4B | |
| SCHEMBL29972743 | 0.83 | ALDH1A1 (0.57) | PKMNPC1RAB9ANAMPTATG4B | |
| SCHEMBL8977667 | 0.81 | ALDH1A1 (0.55) | PKMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL15510403 | 0.79 | MAPT (0.74) | PKMMAPTKDM4EALDH1A1SMN1; SMN2 | |
| Methane SCHEMBL1286316 | 0.78 | ALDH1A1 (0.67) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL11186307 | 0.78 | PKM (0.69) | PKMNPC1RAB9AMAPTKDM4E | |
| SCHEMBL30394839 | 0.77 | MAPT (0.58) | PKMMAPTKDM4EBCL6ALDH1A1 | |
| Methane SCHEMBL18335057 | 0.77 | MDM2 (0.48) | KDM4EALDH1A1KMT2ALMNA | |
| Methane SCHEMBL11774994 | 0.77 | ALDH1A1 (0.64) | NPC1RAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992391-A | PREVENTION AND TREATMENT OF HYPOXIA | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-11-16 | — | — | US | disclosed |