Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525722 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL30394839 | 0.89 | MAPT (0.58) | ALDH1A1MAPTPKMKDM4EKMT2A | |
| Niacinamide SCHEMBL29118200 | 0.87 | F7 (0.67) | ALDH1A1PKMNPC1RAB9ALMNA | |
| SCHEMBL9383012 | 0.85 | PKM (0.56) | ALDH1A1ATG4BMAPTPKMNPC1 | |
| SCHEMBL805874 | 0.84 | LMNA (0.57) | ALDH1A1TAS2R38ATG4BMAPTPKM | |
| SCHEMBL15510403 | 0.83 | MAPT (0.74) | ALDH1A1MAPTPKMKDM4ELMNA | |
| Methane SCHEMBL11836732 | 0.83 | PKM (0.54) | ALDH1A1ATG4BMAPTPKMNPC1 | |
| SCHEMBL23220314 | 0.81 | MAPT (0.61) | ALDH1A1MAPTPKMKDM4EKMT2A | |
| SCHEMBL162008 | 0.80 | RAB9A (0.65) | ALDH1A1TP53HSD17B10MAPTPKM | |
| SCHEMBL14392134 | 0.80 | RAB9A (0.55) | ALDH1A1TP53MAPTPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | disclosed |
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-02-13 | — | — | US | disclosed |
| CN-112105355-B | ABHD12 inhibitors and methods of making and using the same | 斯克利普斯研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-113474383-B | Free radical polymerizable composition | 波林复合材料美国股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-4081296-A1 | DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS | UCB Biopharma SRL (BE) | 2022-11-02 | — | — | EP | disclosed |
| CN-114980975-A | Dihydrocyclopentaisoquinoline sulfonamide derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114845778-A | Dihydrocyclopentaisoquinoline sulfonamide derivative compound | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | ABHD12, SAMHD1, ABHD11 | ALDH1A1 2729/4885TP53 228/4885TYR 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.