Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383012 | 0.83 | PKM (0.56) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| Methane SCHEMBL11836732 | 0.81 | PKM (0.54) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL6963209 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4399387 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1HPGDKDM4EPKMSMN1; SMN2 | |
| SCHEMBL29972743 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL525722 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL14715013 | 0.77 | LMNA (0.43) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL805874 | 0.75 | LMNA (0.57) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL8862853 | 0.75 | BAZ2B (0.46) | ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15510403 | 0.75 | MAPT (0.74) | ALDH1A1HPGDKDM4EPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510344-A | Acrylate fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-04-23 | — | — | US | disclosed |
| EP-0378308-B1 | Acrylate fungicides | AGREVO UK LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5332752-A | Acrylate fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0378308-A1 | Acrylate fungicides | AgrEvo UK Limited (GB) | 1990-07-18 | — | — | EP | disclosed |