Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842799 | 0.85 | LMNA (0.49) | LMNAMAPK1PTGS2KMT2AMAPT | |
| SCHEMBL11837715 | 0.84 | ALDH1A1 (0.38) | LMNAMAPK1MAPTPPARGPPARA | |
| SCHEMBL11838020 | 0.79 | LMNA (0.43) | LMNAMAPK1PTGS2TSHRHPGD | |
| SCHEMBL11843767 | 0.77 | PPARA (0.53) | LMNAMAPK1PTGS2FABP3FABP4 | |
| SCHEMBL11841738 | 0.73 | LMNA (0.57) | LMNAMAPK1PTGS2KMT2AMAPT | |
| SCHEMBL11836770 | 0.73 | PTGS2 (0.37) | LMNAMAPK1PTGS2MAPTPPARG | |
| SCHEMBL11847722 | 0.73 | LMNA (0.52) | LMNAMAPK1PTGS2KMT2AMAPT | |
| SCHEMBL11844358 | 0.72 | LMNA (0.47) | LMNAMAPK1PTGS2FABP3FABP4 | |
| Mandelic Acid SCHEMBL281913 | 0.72 | LMNA (0.78) | LMNAMAPK1HPGDNAAA | |
| SCHEMBL11838727 | 0.71 | LMNA (0.59) | LMNAMAPK1PTGS2KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |