Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840980 | 0.85 | PTGS2 (0.39) | PTGS2SMN1; SMN2MAPTFFAR1MMP1 | |
| SCHEMBL11848052 | 0.84 | MGLL (0.40) | PTGS2FFAR1BCL2ALDH1A1 | |
| SCHEMBL11841735 | 0.73 | PPARG (0.47) | PTGS2SMN1; SMN2MAPTFFAR1PPARG | |
| SCHEMBL11836766 | 0.73 | LMNA (0.45) | PTGS2MAPTHPGDPPARGPPARA | |
| SCHEMBL11837440 | 0.72 | MMP2 (0.42) | PTGS2SMN1; SMN2L3MBTL1MAPTFFAR1 | |
| SCHEMBL11834761 | 0.71 | LMNA (0.44) | PTGS2SMN1; SMN2L3MBTL1MAPTFFAR1 | |
| SCHEMBL11839204 | 0.71 | ACMSD (0.53) | PTGS2MAPTHPGDLMNAMAPK1 | |
| SCHEMBL11848220 | 0.71 | ACLY (0.46) | PTGS2SMN1; SMN2L3MBTL1MAPTFFAR1 | |
| SCHEMBL11841177 | 0.71 | MGLL (0.41) | MMP1MMP2MMP12PPARGPPARA | |
| SCHEMBL11835779 | 0.70 | SLC1A3 (0.47) | SMN1; SMN2L3MBTL1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |