Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833493 | 0.81 | MMP8 (0.40) | LMNAMAPK1ALDH1A1KDM4ERXRA | |
| SCHEMBL11841738 | 0.79 | LMNA (0.57) | LMNAMAPK1PTGS2MAPTTSHR | |
| SCHEMBL11842569 | 0.79 | PTGS2 (0.40) | LMNAMAPK1ALDH1A1PTGS2RXRA | |
| SCHEMBL4909538 | 0.78 | ALDH1A1 (0.46) | LMNAMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL19698852 | 0.77 | MAPT (0.47) | LMNAMAPK1ALDH1A1KDM4EPTGS2 | |
| SCHEMBL11838125 | 0.77 | LMNA (0.59) | LMNAMAPK1PTGS2MAPTTSHR | |
| SCHEMBL11838727 | 0.77 | LMNA (0.59) | LMNAMAPK1ALDH1A1PTGS2TSHR | |
| SCHEMBL2038687 | 0.77 | RXRA (0.47) | ALDH1A1KDM4ERXRARXRBMAPT | |
| SCHEMBL29788057 | 0.77 | RXRA (0.47) | ALDH1A1KDM4ERXRARXRBMAPT | |
| SCHEMBL11843767 | 0.76 | PPARA (0.53) | LMNAMAPK1PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |