Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835902 | 0.88 | BACE1 (0.44) | POLBPPARGPPARAMMP12KMT2A | |
| Hydrochloric Acid SCHEMBL28745095 | 0.84 | ROCK2 (0.50) | ADRB1ADRB3STAT3MMP2MMP3 | |
| SCHEMBL11827837 | 0.83 | PPARG (0.49) | MMP2MMP3GAAPPARGPPARA | |
| SCHEMBL11837086 | 0.82 | BACE1 (0.44) | MMP2GAAMMP12KMT2A | |
| SCHEMBL11823054 | 0.81 | CSNK2A1 (0.53) | ADRB1ADRB3MMP2MMP3MMP12 | |
| SCHEMBL11830550 | 0.81 | FOLH1 (0.46) | MMP2PPARGPPARAMMP12KMT2A | |
| SCHEMBL11829226 | 0.80 | FOLH1 (0.41) | MMP2GAAPPARGPPARAMMP12 | |
| SCHEMBL11821466 | 0.80 | CD274 (0.39) | MMP2MMP3GAAMMP12KMT2A | |
| SCHEMBL11832248 | 0.80 | KMT2A (0.39) | MMP2GAAPPARGPPARAMMP12 | |
| SCHEMBL11828303 | 0.80 | ADAMTS4 (0.41) | MMP2GAAPPARGPPARAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |