Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925566 | 0.94 | SIGMAR1 (0.60) | SIGMAR1S1PR5HRH3LTA4HALDH1A1 | |
| Dimethylformamide SCHEMBL27717638 | 0.84 | KDM4E (0.54) | SIGMAR1S1PR5HRH3LTA4HALDH1A1 | |
| SCHEMBL16582078 | 0.82 | ALDH1A1 (0.64) | SIGMAR1HRH3LTA4HALDH1A1KDM4E | |
| SCHEMBL27658726 | 0.80 | SIGMAR1 (0.58) | SIGMAR1S1PR5HRH3LTA4HALDH1A1 | |
| SCHEMBL2073212 | 0.80 | DRD2 (0.60) | SIGMAR1S1PR5HRH3ALDH1A1KDM4E | |
| SCHEMBL1519223 | 0.80 | MEN1 (0.69) | SIGMAR1S1PR5LTA4HS1PR1MEN1 | |
| SCHEMBL8491424 | 0.79 | HTR2A (0.57) | SIGMAR1S1PR5HRH3LTA4HS1PR4 | |
| SCHEMBL24770743 | 0.79 | ALDH1A1 (0.65) | SIGMAR1S1PR5HRH3LTA4HALDH1A1 | |
| SCHEMBL6994717 | 0.79 | HTR2A (0.64) | SIGMAR1S1PR5KDM4ELMNA | |
| SCHEMBL13236630 | 0.79 | S1PR5 (0.66) | S1PR5HRH3ALDH1A1KDM4ES1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993470-A | ISONIPECOTIC ACID DERIVATIVES, HERBICIDES | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1976-11-23 | — | — | US | disclosed |