Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27589476 | 0.93 | ALDH1A1 (0.49) | KMT2AKDM4EHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL11840447 | 0.90 | ALDH1A1 (0.54) | KMT2AKDM4EHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL27559645 | 0.89 | KMT2A (0.51) | KMT2AKDM4EHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL12811737 | 0.86 | KMT2A (0.71) | KMT2AKDM4EHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL211260 | 0.81 | KMT2A (0.61) | KMT2AKDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL12812270 | 0.80 | ALDH1A1 (0.54) | KMT2AKDM4EHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL29519193 | 0.78 | SMN1; SMN2 (0.54) | KMT2AKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1226530 | 0.78 | SMN1; SMN2 (0.54) | KMT2AKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2837597 | 0.78 | POLB (0.56) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1409830 | 0.78 | KDM4E (0.64) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404595-C | Biaxially oriented polyester film and release film | MITSUBISHI POLYESTER FILM CORP (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-100338126-C | A carbodiimide composition with suppressed yellowing, a stabilizer against hydrolysis and a thermoplastic resin composition | NISSHIN SPINNING (JP) | 2007-09-19 | — | — | CN | disclosed |
| CN-1286892-C | Method for producing ultraviolet absorber composition for thermoplastic polymer | TAKEMOTO OIL & FAT CO LTD (JP) | 2006-11-29 | — | — | CN | disclosed |
| CN-1759137-A | Biaxially oriented polyester film and release film | MITSUBISHI POLYESTER FILM CORP (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1690108-A | Method for producing ultraviolet absorber composition for thermoplastic polymer | TAKEMOTO OIL & FAT CO LTD (JP) | 2005-11-02 | — | — | CN | disclosed |
| CN-1603357-A | A stabilizer against hydrolysis for an ester-group- containing resin and a thermoplastic resin composition | NISSHIN SPINNING (JP) | 2005-04-06 | — | — | CN | disclosed |
| CN-1590439-A | A carbodiimide composition with suppressed yellowing, a stabilizer against hydrolysis and a thermoplastic resin composition | NISSHIN SPINNING (JP) | 2005-03-09 | — | — | CN | disclosed |
| CN-1578832-A | Novel alkaline protease variants and detergents and cleansers containing these novel alkaline protease variants | HENKEL KGAA (DE) | 2005-02-09 | — | — | CN | disclosed |
| CN-1333580-A | Non-aqueous electrochemistry device | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2002-01-30 | — | — | CN | disclosed |
| US-3984556-A | Alkyl-substituted-tricyclic quinazolinones for lowering blood pressure | SANDOZ, INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3982000-A | Alkyl-substituted-tricyclic quinazolinones as bronchodilators | SANDOZ, INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3978059-A | BRONCHODILATOR AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3912731-A | N-substituted anthranilic anhydrides | SANDOZ AG | 1975-10-14 | — | — | US | disclosed |
| US-3905976-A | Substituted tricyclic quinazolinones | SANDOZ AG | 1975-09-16 | — | — | US | disclosed |
| US-3887559-A | Pharmacologically active tricyclic quinazolinones | SANDOZ AG | 1975-06-03 | — | — | US | disclosed |