Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 11/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CTRC | Q99895 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846331 | 0.85 | LMNA (0.56) | TP53CYP3A4THRBALOX15SMN1; SMN2 | |
| SCHEMBL11621974 | 0.83 | TSHR (0.54) | CYP3A4ALOX15SMN1; SMN2TDP1LMNA | |
| SCHEMBL11846316 | 0.81 | F2 (0.44) | TDP1F2NR4A1PRSS2CTRC | |
| SCHEMBL11843357 | 0.80 | ALDH1A1 (0.45) | CYP3A4ALOX15SMN1; SMN2TDP1LMNA | |
| SCHEMBL11852879 | 0.77 | MEN1 (0.56) | TP53CYP3A4THRBALOX15SMN1; SMN2 | |
| SCHEMBL11846744 | 0.77 | ALDH1A1 (0.57) | CYP3A4ALOX15SMN1; SMN2TDP1ALPL | |
| SCHEMBL11841711 | 0.77 | ALPL (0.51) | TP53CYP3A4ALOX15SMN1; SMN2TDP1 | |
| SCHEMBL11856777 | 0.75 | MEN1 (0.58) | SMN1; SMN2TDP1LMNAALPLALPI | |
| SCHEMBL11843404 | 0.74 | APEX1 (0.50) | SMN1; SMN2TDP1LMNAALPLALPI | |
| SCHEMBL11842615 | 0.74 | APEX1 (0.50) | CYP3A4SMN1; SMN2TDP1LMNAALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |