Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843357 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTALPLCYP3A4TDP1 | |
| SCHEMBL11841711 | 0.85 | ALPL (0.51) | ALDH1A1MAPTALPLCYP3A4TDP1 | |
| SCHEMBL11666710 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTALPLCYP3A4TDP1 | |
| SCHEMBL11856777 | 0.81 | MEN1 (0.58) | ALDH1A1MAPTALPLTDP1SMN1; SMN2 | |
| SCHEMBL11848172 | 0.77 | TDP1 (0.57) | ALDH1A1ALPLCYP3A4TDP1ALOX15 | |
| SCHEMBL11841905 | 0.77 | TP53 (0.42) | ALDH1A1MAPTALPLCYP3A4TDP1 | |
| SCHEMBL11842615 | 0.77 | APEX1 (0.50) | ALDH1A1MAPTALPLCYP3A4TDP1 | |
| SCHEMBL11846331 | 0.77 | LMNA (0.56) | ALDH1A1MAPTCYP3A4TDP1ALOX15 | |
| SCHEMBL11847999 | 0.77 | ALPL (0.40) | ALDH1A1MAPTALPLTDP1SMN1; SMN2 | |
| SCHEMBL11846316 | 0.75 | F2 (0.44) | TDP1MEN1ESR1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |