Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399487 | 0.86 | RAB9A (1.00) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL30692090 | 0.86 | RAB9A (1.00) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL11843313 | 0.85 | RAB9A (0.66) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL9598428 | 0.83 | MAPT (0.62) | RAB9ANPC1MAPTHSD17B1KMT2A | |
| SCHEMBL4894905 | 0.82 | ALDH1A1 (0.46) | RAB9ANPC1MAPTHSD17B1ALDH1A1 | |
| SCHEMBL11841857 | 0.81 | MAPT (0.89) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL26575463 | 0.80 | MAPT (0.85) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL407340 | 0.78 | MAPT (0.82) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL26575457 | 0.78 | RAB9A (0.82) | RAB9ANPC1MAPTHSD17B1PGR | |
| SCHEMBL4945231 | 0.78 | HSD17B1 (1.00) | RAB9ANPC1MAPTHSD17B1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939276-A | ANTHRAQUINONES, ASTHMA, ANTIALLERGENS | BURROUGHS WELLCOME CO. (US) | 1976-02-17 | — | — | US | disclosed |