Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP1 | P03956 | 5/20 | 0.49 |
| ▸ | MMP7 | P09237 | 4/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856816 | 0.81 | MMP13 (0.45) | LMNATSHRHSD17B10MMP13MMP1 | |
| SCHEMBL3919696 | 0.77 | LMNA (0.48) | LMNATSHRHSD17B10MMP13MMP1 | |
| SCHEMBL11851149 | 0.77 | MMP13 (0.52) | LMNATSHRHSD17B10MMP13MMP1 | |
| SCHEMBL11845811 | 0.75 | MMP1 (0.41) | LMNAMMP13MMP1MMP7MMP12 | |
| SCHEMBL27182979 | 0.75 | MMP13 (0.57) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL28842545 | 0.74 | MMP13 (0.56) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL6249985 | 0.73 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2POLBCTSK | |
| SCHEMBL27698103 | 0.73 | TSHR (0.56) | LMNATSHRHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL2445638 | 0.73 | MMP13 (0.54) | TSHRMMP13MMP1MMP7MMP12 | |
| SCHEMBL10639322 | 0.72 | ALDH1A1 (0.41) | LMNATSHRHSD17B10MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979471-A | Process for synthesizing ethylenic compounds | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1976-09-07 | — | — | US | disclosed |