Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879281 | 0.85 | MAPT (0.48) | MAPTLMNAHTTGAAPOLB | |
| SCHEMBL11845199 | 0.82 | KDM4E (0.41) | TSHRLMNAGAAPOLBL3MBTL1 | |
| SCHEMBL11849579 | 0.76 | CISD1 (0.48) | TSHRLMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL11842255 | 0.76 | MEN1 (0.54) | TSHRMAPTLMNAHTTGAA | |
| SCHEMBL2883320 | 0.76 | MAPT (0.49) | MAPTLMNAHTTGAAPOLB | |
| SCHEMBL11800233 | 0.75 | PAX8 (0.44) | MAPTLMNAHTTGAAL3MBTL1 | |
| SCHEMBL11851310 | 0.73 | POLB (0.48) | TSHRLMNAPOLBALDH1A1MEN1 | |
| SCHEMBL11841111 | 0.73 | MAPT (0.48) | TSHRMAPTLMNAGAAPOLB | |
| SCHEMBL11842282 | 0.72 | POLB (0.49) | TSHRMAPTLMNAHTTGAA | |
| SCHEMBL16581035 | 0.71 | LMNA (0.51) | TSHRMAPTLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |