SCHEMBL11849148

SCHEMBL11849148

CCOc1ccccc1N1CCN(CCCOc2ccc(F)cc2)CC1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.73
ALDH1A1 P00352 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
MAPT P10636 1/20 0.73
NLRP1 Q9C000 1/20 0.73
DRD2 P14416 9/20 0.65
DRD3 P35462 6/20 0.65
HTR1A P08908 5/20 0.65
HTR2A P28223 4/20 0.65
HRH1 P35367 2/20 0.65
SIGMAR1 Q99720 2/20 0.65
TMEM97 Q5BJF2 1/20 0.65
ADRA1D P25100 1/20 0.61
ADRA1A P35348 1/20 0.61
ADRA1B P35368 1/20 0.61
DRD1 P21728 3/20 0.60
HTR7 P34969 2/20 0.60
DRD5 P21918 2/20 0.60
ADRA2C P18825 1/20 0.60
SLC6A4 P31645 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11850087 0.92 LMNA (0.71) LMNAALDH1A1SMN1; SMN2MAPTNLRP1
Hydrochloric Acid SCHEMBL11846622 0.88 LMNA (0.93) LMNAALDH1A1SMN1; SMN2MAPTNLRP1
SCHEMBL11679660 0.83 DRD2 (0.56) LMNAALDH1A1SMN1; SMN2MAPTNLRP1
SCHEMBL10676614 0.82 DRD2 (0.68) ALDH1A1SMN1; SMN2DRD2DRD3HTR1A
SCHEMBL8828465 0.81 DRD2 (0.64) ALDH1A1SMN1; SMN2DRD2DRD3HTR1A
SCHEMBL1728918 0.80 USP2 (0.78) LMNAALDH1A1DRD2DRD3HTR1A
SCHEMBL246381 0.80 LMNA (0.76) LMNAALDH1A1SMN1; SMN2MAPTNLRP1
SCHEMBL10546259 0.80 DRD2 (0.63) ALDH1A1DRD2DRD3HTR1AHTR2A
SCHEMBL11808577 0.79 CACNA1G (0.66) ALDH1A1SMN1; SMN2MAPTDRD2HTR1A
SCHEMBL16559648 0.78 DRD2 (0.72) LMNAALDH1A1SMN1; SMN2MAPTNLRP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3965106-A 3-Phenoxypropylamine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-22 US disclosed