Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601597 | 0.85 | MLKL (0.77) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL899731 | 0.85 | MLKL (0.77) | MLKLIDO1GAAL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL28259019 | 0.83 | MLKL (0.74) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL11849342 | 0.79 | MLKL (0.51) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL7946544 | 0.75 | IDO1 (0.78) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL28647288 | 0.75 | ALDH1A1 (0.53) | MLKLIDO1GAAL3MBTL1KMT2A | |
| Benzimidazole SCHEMBL10716118 | 0.75 | MLKL (0.62) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL14770661 | 0.73 | MLKL (0.72) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL8154223 | 0.72 | ALDH1A1 (0.53) | MLKLIDO1GAAL3MBTL1KMT2A | |
| SCHEMBL11663293 | 0.71 | IDO1 (0.66) | MLKLIDO1GAAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970535-A | Photopolymerization process utilizing a 2-methyl-substituted benzimidazole as a photosensitizer | SCM CORPORATION (US) | 1976-07-20 | — | — | US | claimed |