Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 3/20 | 0.77 |
| ▸ | IDO1 | P14902 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601597 | 1.00 | MLKL (0.77) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL7946544 | 0.89 | IDO1 (0.78) | MLKLIDO1ALDH1A1POLBGAA | |
| Benzimidazole SCHEMBL10716118 | 0.88 | MLKL (0.62) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL11849336 | 0.85 | MLKL (0.58) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL2720739 | 0.83 | MLKL (0.59) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL14770661 | 0.83 | MLKL (0.72) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL8316457 | 0.82 | MLKL (0.55) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL1349930 | 0.81 | ALDH1A1 (0.61) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL18269212 | 0.81 | MLKL (0.57) | MLKLIDO1ALDH1A1POLBGAA | |
| SCHEMBL18259723 | 0.81 | MLKL (0.69) | MLKLIDO1ALDH1A1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084935-A | Imidazolidinone compound as well as preparation method and application thereof | 贝达药业股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-0599881-B1 | GALLIUM (III) COMPLEXES, PROCESS FOR THEIR OBTENTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | COLLERY PHILIPPE (FR) | 1998-05-13 | — | — | EP | claimed |
| US-3970535-A | Photopolymerization process utilizing a 2-methyl-substituted benzimidazole as a photosensitizer | SCM CORPORATION (US) | 1976-07-20 | — | — | US | claimed |
| CN-122029153-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4626870-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | University of Copenhagen (DK) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| CN-119855820-A | Camptothecins compound and its preparation method and use | 上海齐鲁制药研究中心有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119684998-A | Sandwich structure pressure color-changing film based on double-tricyclic aromatic alkene and preparation method and application thereof | 中山大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-118994190-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118994191-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2024115641-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2024-06-06 | — | — | WO | disclosed |
| US-4564622-A | Triazole derivative as an antiviral agent | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4537776-A | PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0129285-A2 | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0129284-A2 | Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4119478-A | COLORLESS COMPOUND CONTAINING ONE OR MORE BASIC NITROGEN ATOMS ATTACHED TO CARBON IN PYRIDINE OR BENZIMIDAZOLE RING AND HAVING ONE OR MORE UREA OR URETHANE GROUPS | CIBA-GEIGY CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-3970535-A | Photopolymerization process utilizing a 2-methyl-substituted benzimidazole as a photosensitizer | SCM CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
| US-3941788-A | Benzimidazole derivatives | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1976-03-02 | — | — | US | disclosed |