SCHEMBL11852011

SCHEMBL11852011

CCCCCCCCCCCC(=O)OCC(S)CS

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.62
LMNA P02545 2/20 0.60
ALDH1A1 P00352 1/20 0.60
KDM4E B2RXH2 1/20 0.58
DUSP3 P51452 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
DGKA P23743 1/20 0.56
PRKCA P17252 3/20 0.55
PRKCE Q02156 1/20 0.55
PRKCQ Q04759 1/20 0.55
PRKCD Q05655 1/20 0.55
PAM P19021 2/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
ATM Q13315 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
LPAR6 P43657 1/20 0.51
LPAR1 Q92633 1/20 0.51
LPAR4 Q99677 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7797384 0.91 DGKA (0.64) DGKAPRKCAPRKCEPRKCQPRKCD
SCHEMBL27897055 0.85 ALDH1A1 (0.43) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL15741465 0.83 LMNA (0.73) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL6129206 0.83 LMNA (0.73) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL21835883 0.81 LMNA (0.36) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL5576049 0.80 ALDH1A1 (0.81) MAPTLMNAALDH1A1PRKCAPRKCE
SCHEMBL1907725 0.79 MAPT (0.62) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL2397946 0.78 MAPT (0.76) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL2734722 0.78 LMNA (0.83) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL2183839 0.78 LMNA (0.83) MAPTLMNAALDH1A1KDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3959194-B1 PROCESS FOR THE PREPARATION OF COMPOUNDS WITH AT LEAST ONE ALKYLENE GROUP AND AT LEAST ONE THIOL OR THIOLATE GROUP BASF SE (DE) 2025-12-03 EP disclosed
CN-113727965-B Process for the preparation of compounds having at least one alkylene group and at least one thiol or mercapto group 巴斯夫欧洲公司 2024-11-05 CN disclosed
US-11814344-B2 Process for the preparation of compounds with at least one alkylene group and at least one thiol or thiolate group BASF SE (DE) 2023-11-14 US disclosed
US-20220185773-A1 Process for the preparation of compounds with at least one alkylene group and at least one thiol or thiolate group BASF SE (DE) 2022-06-16 US disclosed
EP-3959194-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS WITH AT LEAST ONE ALKYLENE GROUP AND AT LEAST ONE THIOL OR THIOLATE GROUP BASF SE (DE) 2022-03-02 EP disclosed
CN-113727965-A Method for producing compounds having at least one alkylene group and at least one thiol or mercapto group 巴斯夫欧洲公司 2021-11-30 CN disclosed
WO-2020216873-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS WITH AT LEAST ONE ALKYLENE GROUP AND AT LEAST ONE THIOL OR THIOLATE GROUP BASF SE (DE) 2020-10-29 WO disclosed
EP-3730478-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS WITH AT LEAST ONE ALKYLENE GROUP AND AT LEAST ONE THIOL OR THIOLATE GROUP BASF SE (DE) 2020-10-28 EP disclosed
US-3986930-A COLORIMETRY, S-ACYL COMPOUNDS DAINIPPON PHARMACEUTICAL CO., LTD. (JA) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185773-A1 Process for the preparation of compounds with at least one alkylene group and at least one thiol or thiolate group CTH, TMT1A, TST MAPT 1242/4885LMNA 2088/4885ALDH1A1 317/4885
US-11814344-B2 Process for the preparation of compounds with at least one alkylene group and at least one thiol or thiolate group CTH, TMT1A, TST MAPT 1242/4885LMNA 2088/4885ALDH1A1 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.