Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 17/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859729 | 0.82 | OPRM1 (0.49) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11735768 | 0.80 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1GAA | |
| SCHEMBL11845382 | 0.79 | OPRL1 (0.38) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2969459 | 0.73 | OPRL1 (0.39) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL17888234 | 0.73 | OPRM1 (0.62) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL6743192 | 0.71 | OPRM1 (0.39) | OPRL1OPRM1OPRD1OPRK1GAA | |
| SCHEMBL92778 | 0.71 | OPRM1 (0.45) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL16565590 | 0.71 | OPRL1 (0.51) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8049532 | 0.71 | OPRM1 (0.60) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL10515438 | 0.71 | L3MBTL1 (0.49) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |