Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256371 | 0.82 | SLC6A3 (0.47) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL6742634 | 0.80 | SLC6A4 (0.51) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL6743664 | 0.78 | TSHR (0.35) | TSHRSLC6A2SLC6A4SLC6A3CBX7 | |
| Formic Acid SCHEMBL4911299 | 0.74 | KDM4E (0.33) | OPRM1OPRD1OPRK1TSHRHSD11B1 | |
| SCHEMBL11856554 | 0.71 | OPRL1 (0.49) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL7816341 | 0.70 | OPRD1 (0.46) | OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL4824477 | 0.70 | OPRL1 (0.41) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL11859729 | 0.68 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL17888234 | 0.68 | OPRM1 (0.62) | OPRM1OPRD1OPRK1OPRL1MAPK1 | |
| SCHEMBL11830646 | 0.67 | OPRL1 (0.62) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |