Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | PTPRE | P23469 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708749 | 0.83 | SMN1; SMN2 (0.51) | KDM4EHSD17B10KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5490228 | 0.80 | KDM4E (0.57) | KDM4EHSD17B10GRIK1KMT2AMEN1 | |
| SCHEMBL976774 | 0.80 | MPO (0.58) | KDM4EHSD17B10GRIK1KMT2AMEN1 | |
| SCHEMBL1304624 | 0.80 | NEU3 (0.54) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL6891543 | 0.80 | KMT2A (0.55) | KDM4EHSD17B10GRIK1KMT2AMEN1 | |
| SCHEMBL2271365 | 0.79 | PKM (0.70) | KDM4EHSD17B10PTPRCPTPN2PTPN1 | |
| SCHEMBL973761 | 0.79 | ALDH1A1 (0.52) | KDM4EHSD17B10PTPN1KMT2AMEN1 | |
| SCHEMBL11796147 | 0.79 | MPO (0.57) | KDM4EHSD17B10GRIK1KMT2AMEN1 | |
| SCHEMBL3915465 | 0.79 | ALDH1A1 (0.61) | KDM4EHSD17B10GRIK1ALDH1A1POLB | |
| SCHEMBL6750019 | 0.79 | KDM4E (0.75) | KDM4EHSD17B10GRIK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026028-A1 | ANTI-HER3 ANTIBODY AND ANTI-HER3 ANTIBODY-DRUG CONJUGATE AND MEDICAL USE THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| US-10059676-B2 | Process for preparing a novel crystalline form of iodosulfuron-methyl-sodium and use of the same | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) | 2018-08-28 | — | — | US | disclosed |
| US-9700053-B2 | Synergistic herbicidal composition and use thereof | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) | 2017-07-11 | — | — | US | disclosed |
| US-20170118987-A1 | SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF | ROTAM AGROCHEM INTERNATIONAL CO., LTD (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170121294-A1 | PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) | 2017-05-04 | — | — | US | disclosed |
| WO-2017071408-A1 | A SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF | JIANGSU ROTAM CHEMISTRY CO., LTD (CN) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017071410-A1 | PROCESS FOR PREPARING NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2017-05-04 | — | — | WO | disclosed |
| EP-1799684-B1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARM INC (US) | 2014-12-03 | — | — | EP | disclosed |
| EP-1799684-B1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARM INC (US) | 2014-12-03 | — | — | EP | disclosed |
| US-20120178739-A1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-07-12 | — | — | US | disclosed |
| WO-2005028474-A2 | PYRAZOLOQUINOLINE DERIVATIVES AS CHK-1 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0574418-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178739-A1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | PRKCI, PIK3CA, AKT1 | KDM4E 1371/4885HSD17B10 2982/4885PTPRC 896/4885 |
| US-20240026028-A1 | ANTI-HER3 ANTIBODY AND ANTI-HER3 ANTIBODY-DRUG CONJUGATE AND MEDICAL USE THEREOF | ERBB3, EGFR, ERBB2 | KDM4E 1997/4885HSD17B10 2133/4885PTPRC 1065/4885 |
| US-20170121294-A1 | PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME | SCLY, STS, MPST | KDM4E 781/4885HSD17B10 1218/4885PTPRC 1985/4885 |
| US-10059676-B2 | Process for preparing a novel crystalline form of iodosulfuron-methyl-sodium and use of the same | SCLY, STS, MPST | KDM4E 781/4885HSD17B10 1218/4885PTPRC 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.