Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859292 | 0.80 | SIGMAR1 (0.60) | OPRD1KCNH2SIGMAR1 | |
| SCHEMBL11870243 | 0.79 | OPRD1 (0.52) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11858736 | 0.78 | OPRD1 (0.54) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11853407 | 0.78 | SIGMAR1 (0.56) | OPRD1KCNH2SIGMAR1HTR1A | |
| SCHEMBL11684907 | 0.77 | SIGMAR1 (0.70) | OPRD1SIGMAR1PRCP | |
| SCHEMBL11843286 | 0.77 | OPRD1 (0.46) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11682895 | 0.77 | KCNH2 (0.57) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11684960 | 0.77 | OPRD1 (0.57) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11843820 | 0.76 | OPRD1 (0.47) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL10991217 | 0.76 | HTR1A (0.43) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |