Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859455 | 0.87 | DRD2 (0.61) | SIGMAR1KMT2ADRD2 | |
| SCHEMBL11859292 | 0.80 | SIGMAR1 (0.60) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11843820 | 0.79 | OPRD1 (0.47) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11858736 | 0.78 | OPRD1 (0.54) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11857293 | 0.78 | OPRD1 (0.47) | SIGMAR1OPRD1KCNH2HTR1A | |
| SCHEMBL11684907 | 0.77 | SIGMAR1 (0.70) | SIGMAR1OPRD1 | |
| SCHEMBL11682900 | 0.77 | OPRD1 (0.48) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11843286 | 0.77 | OPRD1 (0.46) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11850101 | 0.77 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11681373 | 0.77 | OPRD1 (0.60) | SIGMAR1OPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |