Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537227 | 1.00 | SLC7A5 (0.36) | SLC7A5DPP4DPP7DPP8DPP9 | |
| SCHEMBL756555 | 1.00 | SLC7A5 (0.36) | SLC7A5DPP4DPP7DPP8DPP9 | |
| SCHEMBL3489282 | 0.84 | NOS2 (0.35) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL7536202 | 0.84 | NOS2 (0.35) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL2537702 | 0.84 | NOS2 (0.39) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL139232 | 0.84 | DPP4 (0.35) | DPP4DPP7DPP8DPP9MMP3 | |
| SCHEMBL285831 | 0.84 | NOS2 (0.37) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL15210886 | 0.83 | NOS2 (0.39) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL27646576 | 0.83 | NOS2 (0.39) | DPP4DPP7DPP8DPP9NOS2 | |
| SCHEMBL499450 | 0.83 | NOS2 (0.39) | DPP4DPP7DPP8DPP9NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000139-A | ERGOT ALKALOID INTERMEDIATES | SANDOZ LTD. (CH) | 1976-12-28 | — | — | US | disclosed |