SCHEMBL285831

SCHEMBL285831

N[C@@H](CO)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
PRCP P42785 1/20 0.33
DPP7 Q9UHL4 2/20 0.33
DPP4 P27487 4/20 0.33
DPP8 Q6V1X1 2/20 0.32
DPP9 Q86TI2 2/20 0.32
GLI1 P08151 1/20 0.32
TLR2 O60603 2/20 0.32
ELANE P08246 1/20 0.32
FAP Q12884 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTR2C P28335 1/20 0.30
CTSC P53634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Proline SCHEMBL2588288 0.86 TLR2 (0.30) TLR2
SCHEMBL51271 0.86 NOS2 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL2537702 0.85 NOS2 (0.39) NOS2NOS3NOS1PRCPDPP7
SCHEMBL3489282 0.85 NOS2 (0.35) NOS2NOS3NOS1PRCPDPP7
SCHEMBL7536202 0.85 NOS2 (0.35) NOS2NOS3NOS1PRCPDPP7
SCHEMBL11858950 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL756555 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL1537227 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
Serine SCHEMBL17199761 0.84 ALOX15 (0.41) NOS2NOS3NOS1
SCHEMBL787736 0.82 DPP7 (0.35) NOS2NOS3NOS1PRCPDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197952-A Mutant gene of rice waxy gene Wx and application thereof 重庆市农业科学院 2022-10-18 CN claimed
EP-2528581-B1 METHOD AND COMPOSITIONS FOR THE APPLICATION OF AMINO ACIDS ON THE SKIN THROUGH AN ANHYDROUS MEAN AMBROSIALAB S R L (IT) 2019-11-06 EP claimed
CN-108771168-A A kind of cucumber peel preparation method 广西博白县众旺农产品专业合作社 2018-11-09 CN claimed
EP-2528581-A2 METHOD AND COMPOSITIONS FOR THE APPLICATION OF AMINO ACIDS ON THE SKIN THROUGH AN ANHYDROUS MEAN Ambrosialab S.r.L. (IT) 2012-12-05 EP claimed
WO-2011092581-A2 METHOD AND COMPOSITIONS FOR THE APPLICATION OF AMINO ACIDS ON THE SKIN THROUGH AN ANHYDROUS MEAN AMBROSIALAB S.R.L. (IT) 2011-08-04 WO claimed
US-20110178000-A1 Apoptotically Active Peptides CYTOTOOLS AG (DE) 2011-07-21 US claimed
US-5905142-A Protease resistant PDGF and methods of use ZYMOGENETICS, INC. (US) 1999-05-18 US claimed
US-20240139259-A1 ENZYME AND PROBIOTICS TAKEN WITH PROTEIN, CREATE A WHOLISTIC SYSTEM THAT PREVENTS THE NEGATIVE EFFECTS OF PROTEIN INDIGESTION ON GUT MICROBIOTA, PROMOTE MICROFLORA BALANCE, AND INCREASE THE BIOAVAILABILITY OF POSTBIOTICS ADVANCED ENZYME TECHNOLOGIES LTD. (IN) 2024-05-02 US disclosed
WO-2024079433-A1 PMHC-BINDING HETERODIMERIC RECEPTORS WITH AN IMPROVED DISCRIMINATION BETWEEN A LOW AFFINITY AND A HIGH AFFINITY PMHC AND THAT DO NOT ASSOCIATED WITH CD3 OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-04-18 WO disclosed
US-20230270876-A1 SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES NOVARTIS AG (CH) 2023-08-31 US disclosed
CN-113166034-B Diester compounds as pro-fragrances 长谷川香料株式会社 2023-08-15 CN disclosed
US-11596695-B2 Specific sites for modifying antibodies to make immunoconjugates NOVARTIS AG (CH) 2023-03-07 US disclosed
CN-115197952-A Mutant gene of rice waxy gene Wx and application thereof 重庆市农业科学院 2022-10-18 CN disclosed
EP-1541169-A1 Use of limk-1, its analogues and ligands for the production of a medicament against a thrombus formation of blood clotting disease Aventis Pharma Deutschland GmbH (DE) 2005-06-15 EP disclosed
CN-1468317-A Use of multiple recombination sites with unique specificity in recombinant cloning ά 2004-01-14 CN disclosed
US-20030215833-A1 Variant cleavage stimulation factor and its encoding nucleic acid TEXAS TECH UNIVERSITY 2003-11-20 US disclosed
WO-2001011065-A2 HEPATITIS A VIRUS CLONES ADAPTED FOR GROWTH IN AGMK CELLS THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-02-15 WO disclosed
EP-0576669-A4 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORP (US) 1996-05-08 EP disclosed
EP-0576669-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1994-01-05 EP disclosed
WO-1993013794-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1993-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270876-A1 SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES PTMS, FCGR2A, FCGR3B NOS2 4527/4885NOS3 4571/4885NOS1 4769/4885
US-11596695-B2 Specific sites for modifying antibodies to make immunoconjugates PTMS, FCGR2A, FCGR3B NOS2 4527/4885NOS3 4571/4885NOS1 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.