SCHEMBL756555

SCHEMBL756555

CC(C)C[C@H](N)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.36
DPP4 P27487 4/20 0.35
DPP7 Q9UHL4 2/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
NOS2 P35228 2/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
PRCP P42785 1/20 0.34
TLR2 O60603 2/20 0.32
MMP3 P08254 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537227 1.00 SLC7A5 (0.36) SLC7A5DPP4DPP7DPP8DPP9
SCHEMBL11858950 1.00 SLC7A5 (0.36) SLC7A5DPP4DPP7DPP8DPP9
SCHEMBL3489282 0.84 NOS2 (0.35) DPP4DPP7DPP8DPP9NOS2
SCHEMBL7536202 0.84 NOS2 (0.35) DPP4DPP7DPP8DPP9NOS2
SCHEMBL2537702 0.84 NOS2 (0.39) DPP4DPP7DPP8DPP9NOS2
SCHEMBL139232 0.84 DPP4 (0.35) DPP4DPP7DPP8DPP9MMP3
SCHEMBL285831 0.84 NOS2 (0.37) DPP4DPP7DPP8DPP9NOS2
SCHEMBL15210886 0.83 NOS2 (0.39) DPP4DPP7DPP8DPP9NOS2
SCHEMBL27646576 0.83 NOS2 (0.39) DPP4DPP7DPP8DPP9NOS2
SCHEMBL499450 0.83 NOS2 (0.39) DPP4DPP7DPP8DPP9NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111000997-A Method for treating osteogenesis imperfecta 建新公司 2020-04-14 CN claimed
US-10155952-B2 Method for producing target substance AJINOMOTO CO., INC. (JP) 2018-12-18 US claimed
US-10024859-B2 Markers for detection of gastric cancer PACIFIC EDGE LIMITED (NZ) 2018-07-17 US claimed
US-20170292956-A1 Markers for Detection of Gastric Cancer PACIFIC EDGE LIMITED (NZ) 2017-10-12 US claimed
CN-102459646-B The detection mark of gastric cancer 环太平洋生物技术有限公司 2016-08-10 CN claimed
CN-105765067-A Modified beta-galactosidase 天野酶株式会社 2016-07-13 CN claimed
US-9310370-B2 Markers for detection of gastric cancer PACIFIC EDGE LIMITED (NZ) 2016-04-12 US claimed
EP-2430193-B1 MARKERS FOR DETECTION OF GASTRIC CANCER PACIFIC EDGE LTD (NZ) 2016-03-09 EP claimed
CN-105316405-A Markers for detection of gastric cancer PACIFIC EDGE BIOTECHNOLOGY LTD 2016-02-10 CN claimed
US-20120135881-A1 MARKERS FOR DETECTION OF GASTRIC CANCER GUILFORD PARRY JOHN (NZ) 2012-05-31 US claimed
EP-2430193-A1 MARKERS FOR DETECTION OF GASTRIC CANCER Pacific Edge Biotechnology Limited (NZ) 2012-03-21 EP claimed
WO-2010131984-A1 MARKERS FOR DETECTION OF GASTRIC CANCER PACIFIC EDGE BIOTECHNOLOGY LIMITED (NZ) 2010-11-18 WO claimed
US-20090175811-A1 USE OF COMPOUND THAT INACTIVATES PROTEIN KINASE A IN A COMPOSITION CONTAINING A COSMETICALLY ACCEPTABLE MEDIUM FOR LIGHTENING THE SKIN SOCIETE D'EXPLOITATION DE PRODUCTS LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2009-07-09 US claimed
EP-1292615-B1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH CORP (US) 2006-10-25 EP claimed
US-20050118119-A1 Use of a compound inactivating the kinase a protein in a composition containg a cosmetically acceptable medium in order to lighten the skin SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES (SEPPIC) (FR) 2005-06-02 US claimed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US claimed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US claimed
EP-0782581-A4 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES BAYER AG (US) 2000-05-31 EP claimed
EP-0782581-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES Bayer Corporation (US) 1997-07-09 EP claimed
WO-1996009317-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES BAYER CORPORATION (US) 1996-03-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090175811-A1 USE OF COMPOUND THAT INACTIVATES PROTEIN KINASE A IN A COMPOSITION CONTAINING A COSMETICALLY ACCEPTABLE MEDIUM FOR LIGHTENING THE SKIN PRKACA, PRKACB, PRKACG SLC7A5 4679/4885DPP4 4442/4885DPP7 3968/4885
US-20050118119-A1 Use of a compound inactivating the kinase a protein in a composition containg a cosmetically acceptable medium in order to lighten the skin PRKACG, PRKACA, PRKACB SLC7A5 4608/4885DPP4 4639/4885DPP7 4149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.