SCHEMBL2537702

SCHEMBL2537702

NC(=O)C[C@H](N)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
GLI1 P08151 1/20 0.33
PRCP P42785 1/20 0.32
DPP7 Q9UHL4 2/20 0.32
DPP4 P27487 4/20 0.31
DPP8 Q6V1X1 2/20 0.31
DPP9 Q86TI2 2/20 0.31
TLR2 O60603 2/20 0.30
ELANE P08246 1/20 0.30
FAP Q12884 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3489282 0.88 NOS2 (0.35) NOS2NOS3NOS1GLI1PRCP
SCHEMBL7536202 0.88 NOS2 (0.35) NOS2NOS3NOS1GLI1PRCP
SCHEMBL1275426 0.86 ALOX15 (0.38) NOS2NOS3NOS1GLI1PRCP
SCHEMBL285831 0.85 NOS2 (0.37) NOS2NOS3NOS1GLI1PRCP
SCHEMBL11484027 0.85 NOS2 (0.36) NOS2NOS3NOS1GLI1PRCP
SCHEMBL11559258 0.84 NOS2 (0.38) NOS2NOS3NOS1GLI1PRCP
SCHEMBL1537227 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL11858950 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL756555 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL51271 0.84 NOS2 (0.36) NOS2NOS3NOS1GLI1PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567559-A Peptide with anti-forgetting activity and preparation method and application thereof 安琪生物科技有限公司 2024-02-20 CN disclosed
CN-117486971-A Antioxidant peptide, walnut peptide and preparation method and application thereof 安琪生物科技有限公司 2024-02-02 CN disclosed
US-20210024593-A1 MODIFIED HEAT SHOCK PROTEINS RUBICON BIOTECHNOLOGY LLC 2021-01-28 US disclosed
EP-3672985-A2 MODIFIED HEAT SHOCK PROTEINS Rubicon Biotechnology LLC (US) 2020-07-01 EP disclosed
WO-2019040887-A2 MODIFIED HEAT SHOCK PROTEINS RUBICON BIOTECHNOLOGY LLC (US) 2019-02-28 WO disclosed
US-8044230-B2 Hydrolytic stability needed to maintain the prodrug in solution in the subject's system until appropriate conditions exist when the prodrug can hydrolyze, releasing the active compound INTERVET INC. (US) 2011-10-25 US disclosed
US-20080146640-A1 Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof SCHERING-PLOUGH LTD. (CH) 2008-06-19 US disclosed
WO-2005080551-A2 STEM CELLS UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2005-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146640-A1 Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof TREH, ADH5, CES2 NOS2 286/4885NOS3 335/4885NOS1 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.