Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112571 | 0.84 | HTT (0.52) | BACE1HSPA5POLBHTTMEN1 | |
| SCHEMBL28505038 | 0.80 | PTPN1 (0.44) | BACE1POLBHTTMEN1KMT2A | |
| SCHEMBL11803532 | 0.77 | HTT (0.42) | BACE1HSPA5POLBHTTMEN1 | |
| SCHEMBL2174289 | 0.77 | TRPA1 (0.48) | TRPA1BACE1HSPA5POLBHTT | |
| SCHEMBL10824494 | 0.77 | HTT (0.47) | BACE1HSPA5POLBHTTMEN1 | |
| SCHEMBL5195249 | 0.77 | ALOX15 (0.50) | TRPA1BACE1HSPA5HTTMEN1 | |
| SCHEMBL9976443 | 0.77 | ALDH1A1 (0.38) | BACE1HSPA5POLBHTTMEN1 | |
| SCHEMBL1988566 | 0.76 | TRPA1 (0.46) | TRPA1BACE1HSPA5HTTMEN1 | |
| SCHEMBL9853387 | 0.76 | ALDH1A1 (0.50) | BACE1HSPA5POLBHTTMEN1 | |
| SCHEMBL19972023 | 0.76 | HTT (0.41) | BACE1HSPA5POLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
| US-20110030151-A1 | COMPOSITIONS COMPRISING DISCRETE PARTICLES AGGREGATES AND DISCRETE PARTICLE AGGLOMERATES FOR APPLICATION TO KERATIN FIBERS | TREMBLAY MARIO ELMEN | 2011-02-10 | — | — | US | disclosed |
| US-7695525-B2 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| EP-1634572-B1 | Hair dyeing compositions comprising 2-Amino-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20060248663-A1 | Compositions comprising discrete particles aggregates and discrete particle agglomerates for application to keratin fibers | THE PROCTER & GAMBLE COMPANY | 2006-11-09 | — | — | US | disclosed |
| EP-1634572-A1 | Hair dyeing compositions comprising 2-(Amino or substituted Amino)-3-5-substituted phenol compounds and use thereof | The Procter and Gamble Company (US) | 2006-03-15 | — | — | EP | disclosed |
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | KRT18, TYR, TH | TRPA1 754/4885BACE1 2869/4885HSPA5 2685/4885 |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | TRPA1 2253/4885BACE1 2671/4885HSPA5 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.