Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | TDO2 | P48775 | 8/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132450 | 0.80 | PDGFRB (0.56) | IMPDH2CYP2A6PDGFRBPDGFRATDO2 | |
| SCHEMBL11871562 | 0.78 | CSNK2A2 (0.41) | NR4A2PIM1MAPTNPSR1MEN1 | |
| SCHEMBL8730331 | 0.74 | IMPDH2 (0.65) | IMPDH2CYP2A6PDGFRBPDGFRATDO2 | |
| SCHEMBL29713619 | 0.74 | TDO2 (0.70) | IMPDH2PDGFRBPDGFRATDO2ALOX5 | |
| SCHEMBL28928045 | 0.73 | NR4A2 (0.62) | IMPDH2CYP2A6PDGFRBPDGFRATDO2 | |
| SCHEMBL10227492 | 0.73 | AXL (0.58) | IMPDH2CYP2A6PDGFRBPDGFRATDO2 | |
| SCHEMBL15333384 | 0.72 | MAOB (0.59) | IMPDH2PDGFRBPDGFRATDO2ALOX5 | |
| SCHEMBL5259184 | 0.72 | NR4A2 (0.60) | IMPDH2CYP2A6TDO2ALOX5NR4A2 | |
| 3-Formylindole SCHEMBL56373 | 0.71 | CYP2A6 (1.00) | IMPDH2CYP2A6PDGFRBPDGFRAPRKD3 | |
| 3-Formylindole SCHEMBL38654556 | 0.71 | CYP2A6 (1.00) | IMPDH2CYP2A6PDGFRBPDGFRAPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983137-A | Process for preparing 3-(indol-3-yl)-dehydronaphthalide hydrochlorides | POLAROID CORPORATION (US) | 1976-09-28 | — | — | US | claimed |
| US-3983137-A | Process for preparing 3-(indol-3-yl)-dehydronaphthalide hydrochlorides | POLAROID CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983137-A | Process for preparing 3-(indol-3-yl)-dehydronaphthalide hydrochlorides | POLAROID CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3933854-A | CHEMICAL INTERMEDIATES FOR INDICATOR DYES | POLAROID CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933854-A | CHEMICAL INTERMEDIATES FOR INDICATOR DYES | POLAROID CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |