Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 6/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12318716 | 0.84 | NPC1 (0.46) | RAB9ADRD2KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1186729 | 0.84 | SMN1; SMN2 (0.49) | RAB9ASYKKDM4ESMN1; SMN2MAPT | |
| SCHEMBL2405841 | 0.81 | FFAR1 (0.40) | RAB9ASYKABCB1HTR1ADRD2 | |
| SCHEMBL12266351 | 0.81 | SYK (0.50) | RAB9ASYKGABRA1GABRG2GABRB3 | |
| SCHEMBL2408409 | 0.80 | CYP11B1 (0.42) | ABCB1KDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2411928 | 0.80 | LYPLA1 (0.52) | RAB9ASYKABCB1HTR1ADRD2 | |
| SCHEMBL12266314 | 0.79 | TSHR (0.45) | RAB9ASYKABCB1HTR1ADRD2 | |
| SCHEMBL12270684 | 0.79 | SYK (0.45) | RAB9ASYKGABRA1GABRG2GABRB3 | |
| SCHEMBL12266348 | 0.78 | ALDH1A1 (0.47) | RAB9ASYKKDM4ESMN1; SMN2MAPT | |
| SCHEMBL12314717 | 0.78 | PTPRA (0.40) | RAB9ASYKABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888356-B2 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2011-02-15 | — | — | US | claimed |
| US-7652000-B2 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1980564-A1 | Antibiotics containing borinic acid complexes and methods of use | Anacor Pharmaceuticals, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| US-7393856-B2 | Anti-viral uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20080146803-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. | 2008-06-19 | — | — | US | disclosed |
| EP-1581500-A4 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS INC (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1771182-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | Anacor Pharmaceuticals, Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1765360-A2 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1765358-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006085932-A2 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-26 | — | — | US | disclosed |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-19 | — | — | US | disclosed |
| US-20060009422-A1 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. | 2006-01-12 | — | — | US | disclosed |
| WO-2005123094-A2 | TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005123095-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-1581500-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | Anacor Pharmaceuticals, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040224923-A1 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. | 2004-11-11 | — | — | US | disclosed |
| WO-2004056322-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224923-A1 | Antibiotics containing borinic acid complexes and methods of use | BPGM, BROX, TBCA | RAB9A 2198/4885SYK 4070/4885GABRA1 65/4885 |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | BPGM, HRH1, HRH3 | RAB9A 2635/4885SYK 4264/4885GABRA1 62/4885 |
| US-20060009422-A1 | Boron-containing compounds and methods of use | BROX, BTD, PBDC1 | RAB9A 2857/4885SYK 3645/4885GABRA1 197/4885 |
| US-20080146803-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | BPGM, BROX, TBCA | RAB9A 2198/4885SYK 4070/4885GABRA1 65/4885 |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | SSB, BPGM, HAVCR2 | RAB9A 3638/4885SYK 4769/4885GABRA1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.