Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.98 |
| ▸ | DRD2 | P14416 | 2/20 | 0.98 |
| ▸ | HTR2A | P28223 | 2/20 | 0.98 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.98 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.98 |
| ▸ | CNR1 | P21554 | 1/20 | 0.98 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.98 |
| ▸ | HTR2C | P28335 | 1/20 | 0.98 |
| ▸ | HTR7 | P34969 | 1/20 | 0.98 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.98 |
| ▸ | HRH1 | P35367 | 1/20 | 0.98 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.98 |
| ▸ | DRD3 | P35462 | 1/20 | 0.98 |
| ▸ | HTR2B | P41595 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11880141 | 0.99 | ALDH1A1 (0.98) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Buspirone SCHEMBL16398 | 0.99 | HTR1A (1.00) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Buspirone SCHEMBL17004050 | 0.99 | HTR1A (1.00) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Buspirone SCHEMBL41495 | 0.98 | ALDH1A1 (1.00) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| SCHEMBL11875965 | 0.98 | HTR1A (0.98) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Buspirone SCHEMBL41496 | 0.98 | HTR1A (0.98) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Buspirone SCHEMBL10441318 | 0.98 | ALDH1A1 (1.00) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Hydrochloric Acid SCHEMBL11878911 | 0.96 | ALDH1A1 (0.98) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| SCHEMBL11881209 | 0.96 | HTR1A (0.95) | HTR1AALDH1A1DRD2HTR2ASLC22A2 | |
| Hydrochloric Acid SCHEMBL11877578 | 0.95 | ALDH1A1 (0.95) | HTR1AALDH1A1DRD2HTR2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976776-A | Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones | MEAD JOHNSON & COMPANY (US) | 1976-08-24 | — | — | US | claimed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | HTR1A 7/4885ALDH1A1 2581/4885DRD2 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.