SCHEMBL201736

SCHEMBL201736

Fc1ccc(-c2nc(CCl)cs2)cc1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.72
POLB P06746 4/20 0.66
RAB9A P51151 3/20 0.66
NPC1 O15118 2/20 0.66
GAA P10253 2/20 0.66
KDM4E B2RXH2 6/20 0.62
ALDH1A1 P00352 6/20 0.62
TDP1 Q9NUW8 4/20 0.62
LMNA P02545 4/20 0.62
MAPT P10636 4/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.51
AR P10275 1/20 0.51
HPGD P15428 1/20 0.51
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203617 0.84 GFER (1.00) GFERPOLBRAB9ANPC1GAA
SCHEMBL2226112 0.82 LMNA (0.67) GFERPOLBGAAKDM4EALDH1A1
SCHEMBL2225013 0.82 LMNA (0.62) GFERPOLBRAB9ANPC1GAA
SCHEMBL19031364 0.82 GFER (0.72) GFERPOLBRAB9ANPC1GAA
SCHEMBL201539 0.82 GFER (0.72) GFERPOLBRAB9ANPC1GAA
SCHEMBL2706140 0.82 GFER (0.72) GFERPOLBRAB9ANPC1GAA
SCHEMBL19031390 0.82 GFER (0.72) GFERPOLBRAB9ANPC1GAA
SCHEMBL28842593 0.81 GFER (0.71) GFERPOLBRAB9ANPC1GAA
SCHEMBL5385321 0.81 GFER (0.71) GFERPOLBRAB9ANPC1GAA
SCHEMBL118764 0.81 GFER (0.71) GFERPOLBRAB9ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3394054-B1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL SCIENT IND RES (IN) 2019-11-06 EP claimed
US-10246449-B2 1,2,3 triazole-thiazole compounds, process for preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-04-02 US claimed
US-20180370962-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-12-27 US claimed
EP-3394054-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF Council of Scientific and Industrial Research (IN) 2018-10-31 EP claimed
WO-2017109793-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-06-29 WO claimed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
EP-3394054-B1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL SCIENT IND RES (IN) 2019-11-06 EP disclosed
US-10246449-B2 1,2,3 triazole-thiazole compounds, process for preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-04-02 US disclosed
US-20180370962-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-12-27 US disclosed
EP-3394054-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF Council of Scientific and Industrial Research (IN) 2018-10-31 EP disclosed
WO-2017109793-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-06-29 WO disclosed
EP-2533783-B1 COMPOUNDS AND METHODS for the inhibition of HDAC TEMPERO PHARMACEUTICALS INC (US) 2015-11-04 EP disclosed
US-6933322-B2 Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus WYETH (US) 2005-08-23 US disclosed
US-6930131-B2 Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM) WYETH (US) 2005-08-16 US disclosed
US-20030216442-A1 Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus WYETH 2003-11-20 US disclosed
US-20030203941-A1 Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus WYETH (US) 2003-10-30 US disclosed
US-5573999-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
US-5538940-A FUNGICIDE, MITICIDE, INSECTICIDE BASF AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0525516-B1 Derivatives of beta substituted cinnomic acid BASF AG (DE) 1995-09-27 EP disclosed
EP-0525516-A2 Derivatives of beta substituted cinnomic acid BASF Aktiengesellschaft (DE) 1993-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180370962-A1 NOVEL 1,2,3 TRIAZOLE-THIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF TYR, JAK1, JAK3 GFER 3832/4885POLB 1081/4885RAB9A 890/4885
US-20030203941-A1 Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus GPR119, INSR, SLC5A1 GFER 3972/4885POLB 3924/4885RAB9A 1828/4885
US-20030216442-A1 Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus INSR, GPR119, SLC5A1 GFER 4211/4885POLB 3379/4885RAB9A 1302/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 GFER 137/4885POLB 364/4885RAB9A 2799/4885
US-10246449-B2 1,2,3 triazole-thiazole compounds, process for preparation and use thereof TYR, JAK1, JAK3 GFER 3792/4885POLB 834/4885RAB9A 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.