Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921514 | 0.89 | MAPT (0.46) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL793546 | 0.87 | BCHE (0.56) | ACHEBCHEMEN1KMT2ANR1I2 | |
| SCHEMBL9979912 | 0.85 | MAPT (0.43) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL6940359 | 0.83 | BCHE (0.53) | ACHEBCHEMEN1KMT2ANR1I2 | |
| SCHEMBL4251581 | 0.81 | DNM1 (0.39) | MAPTKDM4EMAPK1HTTALDH1A1 | |
| SCHEMBL1923381 | 0.80 | GPR3 (0.64) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL13374193 | 0.80 | ALDH1A1 (0.41) | ACHEBCHEMEN1KMT2ANR1I2 | |
| SCHEMBL2721451 | 0.79 | ALDH1A1 (0.41) | MAPTKDM4EMAPK1IDO1ALDH1A1 | |
| SCHEMBL14845769 | 0.79 | ALDH1A1 (0.41) | MAPTKDM4EMAPK1HTTALDH1A1 | |
| SCHEMBL19114130 | 0.79 | MAPT (0.47) | MEN1KMT2AMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135809-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-05-09 | — | — | US | disclosed |
| US-20190135809-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-05-09 | — | — | US | disclosed |
| US-20170305906-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-10-26 | — | — | US | disclosed |
| US-20170305906-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-10-26 | — | — | US | disclosed |
| US-20170305906-A1 | Pro-Neurogenic Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-10-26 | — | — | US | disclosed |
| US-9701676-B2 | Pro-neurogenic compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701676-B2 | Pro-neurogenic compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701676-B2 | Pro-neurogenic compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2887803-A1 | PRO-NEUROGENIC COMPOUNDS | Board of Regents of the University of Texas System (US) | 2015-07-01 | — | — | EP | disclosed |
| US-20140057900-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057900-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057900-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2014031986-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014031986-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | WO | disclosed |
| US-20120108499-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2012-05-03 | — | — | US | disclosed |
| US-20100167995-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2010-07-01 | — | — | US | disclosed |
| US-7612036-B2 | Peptoid compounds | UNIVERSITY OF WOLLONGONG (AU) | 2009-11-03 | — | — | US | disclosed |
| US-20070111927-A1 | Peptoid compounds | UNIVERSITY OF WOLLONGONG (AU) | 2007-05-17 | — | — | US | disclosed |
| US-7160854-B2 | Binaphthyl peptidomimetics for treating vancomycin resistant Staphylococcus aureas infections | UNIVERSITY OF WOLLONGONG (AU) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108499-A1 | PEPTOID COMPOUNDS | VIP, FPR1, VIPR1 | ACHE 4871/4885BCHE 3785/4885MEN1 3065/4885 |
| US-20100167995-A1 | PEPTOID COMPOUNDS | VIP, FPR1, VIPR1 | ACHE 4871/4885BCHE 3785/4885MEN1 3065/4885 |
| US-20140057900-A1 | Pro-Neurogenic Compounds | BDNF, NES, DCX | ACHE 198/4885BCHE 539/4885MEN1 3415/4885 |
| US-20190135809-A1 | Pro-Neurogenic Compounds | BDNF, NES, DCX | ACHE 198/4885BCHE 539/4885MEN1 3415/4885 |
| US-20070111927-A1 | Peptoid compounds | VIP, FPR1, VIPR1 | ACHE 4871/4885BCHE 3785/4885MEN1 3065/4885 |
| US-20170305906-A1 | Pro-Neurogenic Compounds | BDNF, NES, DCX | ACHE 198/4885BCHE 539/4885MEN1 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.