Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398807 | 0.71 | CA12 (0.45) | GPR3CA2CA9CA12CA1 | |
| SCHEMBL88858 | 0.71 | CA12 (0.45) | GPR3CA2CA9CA12CA1 | |
| Hydrochloric Acid SCHEMBL9756819 | 0.70 | CA12 (0.44) | GPR3CA2CA9CA12CA1 | |
| SCHEMBL28201382 | 0.70 | CA12 (0.44) | GPR3CA2CA9CA12CA1 | |
| SCHEMBL574097 | 0.70 | GPR3 (0.46) | GPR3CA2CA9CA12CA1 | |
| SCHEMBL8879355 | 0.69 | PKM (0.33) | GPR3CA2CA9CA12CA1 | |
| SCHEMBL29695488 | 0.68 | ALDH1A1 (0.50) | GPR3ALDH1A1KCNA3PKMKDM4E | |
| SCHEMBL299692 | 0.68 | ALDH1A1 (0.50) | GPR3ALDH1A1KCNA3PKMKDM4E | |
| SCHEMBL8586201 | 0.67 | GPR3 (0.43) | GPR3CA2CA9CA12CA1 | |
| Isobutane SCHEMBL9756824 | 0.65 | CA12 (0.40) | GPR3CA2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3891637-A | Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides | PFIZER | 1975-06-24 | — | — | US | disclosed |