Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203821 | 0.91 | TRHR (0.46) | TRHR | |
| SCHEMBL4956842 | 0.91 | TRHR (0.46) | TRHR | |
| SCHEMBL11203817 | 0.91 | TRHR (0.46) | TRHR | |
| SCHEMBL11308638 | 0.85 | TRHR (0.42) | TRHR | |
| SCHEMBL11882559 | 0.84 | REN (0.47) | — | |
| SCHEMBL11308630 | 0.84 | ACE (0.45) | TRHR | |
| SCHEMBL11796296 | 0.83 | TRHR (0.39) | TRHR | |
| SCHEMBL30798884 | 0.82 | OPRM1 (0.51) | — | |
| SCHEMBL1372319 | 0.82 | TRHR (0.46) | TRHR | |
| SCHEMBL11798918 | 0.82 | CTSL (0.39) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3860570-A | TRIPEPTIDE INTERMEDIATE FOR MAKING TRH | ABBOTT LAB | 1975-01-14 | — | — | US | disclosed |