Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29910198 | 0.86 | NPC1 (0.41) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL11410077 | 0.80 | RAB9A (0.40) | TSHRRAB9APKMNPC1HTT | |
| SCHEMBL11405715 | 0.79 | NPC1 (0.43) | TSHRRAB9APKMNPC1GAA | |
| SCHEMBL11146268 | 0.78 | SMN1; SMN2 (0.44) | RAB9ANPC1GAAHTTSMN1; SMN2 | |
| SCHEMBL13724343 | 0.76 | TDP1 (0.46) | RAB9ANPC1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL691644 | 0.76 | TSHR (0.46) | TSHRRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL14520272 | 0.76 | ALDH1A1 (0.46) | TSHRRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL812574 | 0.74 | RAB9A (0.64) | RAB9ANPC1GAAHTTSMN1; SMN2 | |
| SCHEMBL11421289 | 0.74 | KCNH3 (0.50) | RAB9ANPC1GAAHTTALDH1A1 | |
| SCHEMBL12200621 | 0.74 | NPC1 (0.33) | RAB9ANPC1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596923-A | Substituted 5-(cyclohex-2-en-1-yl)-penta-2,4-dienes and 5-(cyclohex-2-en-1-yl)-pent-2-en-4-ines as active agents against abiotic stress in plants | BAYER CROPSCIENCE AG | 2014-02-19 | — | — | CN | disclosed |
| US-20110155660-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2011-06-30 | — | — | US | disclosed |
| US-7882963-B2 | modifying polyamide discriminating layer ( e.g metaphenylene diamine- trimesoyl chloride monomers) with aminoacetophenone or aminothiophenol; fouling resistant surface, improved salt rejection, antimicrobial properties, improved solute, and/or small organics rejection; for water purification | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20090159527-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2009-06-25 | — | — | US | disclosed |
| WO-2007133362-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| EP-0053713-A1 | Process for preparing 1-acetylamino-4-chloro-2,5 dimethoxybenzene | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-16 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| EP-0001994-A1 | Process for preparing acetylaminobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-30 | — | — | EP | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |