Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 9/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29910198 | 0.88 | NPC1 (0.41) | RECQLTHRBHPGDTP53ALOX15 | |
| SCHEMBL11178475 | 0.87 | TSHR (0.67) | TSHRALDH1A1HSD17B10CYP3A4ALOX15 | |
| SCHEMBL14590749 | 0.81 | TSHR (0.43) | TSHRALDH1A1RECQLHSD17B10THRB | |
| SCHEMBL11146268 | 0.80 | SMN1; SMN2 (0.44) | RECQLTHRBTP53KIF11MAPT | |
| SCHEMBL153943 | 0.78 | TSHR (0.67) | TSHRALDH1A1RECQLHSD17B10THRB | |
| SCHEMBL13724343 | 0.78 | TDP1 (0.46) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL14520272 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1RECQLHSD17B10THRB | |
| SCHEMBL12200621 | 0.76 | NPC1 (0.33) | RECQLTHRBMAPTNPC1RAB9A | |
| SCHEMBL11421289 | 0.76 | KCNH3 (0.50) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL1189234 | 0.76 | HPGD (0.48) | TSHRTHRBHPGDCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-10-05 | — | — | US | claimed |
| EP-4237405-A1 | 2-METHOXYMETHYL-P-PHENYLENEDIAMINE IN COSMETIC GRADE QUALITY | Wella Germany GmbH (DE) | 2023-09-06 | — | — | EP | claimed |
| US-11517514-B2 | Resorcinol-free hair colouring compositions | BEAUTY & BUSINESS S.P.A. (IT) | 2022-12-06 | — | — | US | claimed |
| EP-4066812-A1 | RESORCINOL-FREE HAIR COLOURING COMPOSITIONS | Beauty & Business S.p.A. (IT) | 2022-10-05 | — | — | EP | claimed |
| US-20220304908-A1 | RESORCINOL-FREE HAIR COLOURING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2022-09-29 | — | — | US | claimed |
| WO-2022090235-A1 | 2-METHOXYMETHYL-P-PHENYLENEDIAMINE IN COSMETIC GRADE QUALITY | WELLA GERMANY GMBH (DE) | 2022-05-05 | — | — | WO | claimed |
| US-11285091-B2 | M-aminophenol-free hair-colouring compositions | BEAUTY & BUSINESS S.P.A. (IT) | 2022-03-29 | — | — | US | claimed |
| US-20210177717-A1 | M-AMINOPHENOL-FREE HAIR-COLOURING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2021-06-17 | — | — | US | claimed |
| EP-2103299-B1 | Oxidizing hair colourant compositions | PROCTER & GAMBLE (US) | 2013-02-27 | — | — | EP | claimed |
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| US-7988740-B2 | Keratin dyeing compositions comprising a radical scavenger and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-02 | — | — | US | claimed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | claimed |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | claimed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | claimed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| US-7597720-B2 | Oxidizing hair colourant compositions | THE PROCTER & GAMBLE COMPANY (US) | 2009-10-06 | — | — | US | claimed |
| EP-2103299-A2 | Oxidizing hair colourant compositions | The Procter and Gamble Company (US) | 2009-09-23 | — | — | EP | claimed |
| US-20090119852-A1 | Oxidizing Hair Colourant Compositions | WELLA OPERATIONS US, LLC | 2009-05-14 | — | — | US | claimed |
| WO-2009060334-A2 | OXIDIZING HAIR COLOURANT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090119852-A1 | Oxidizing Hair Colourant Compositions | TET1, TET2, TET3 | TSHR 2249/4885ALDH1A1 533/4885RECQL 3341/4885 |
| US-20110035885-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof | KRT18, LPO, CYB5R3 | TSHR 4803/4885ALDH1A1 326/4885RECQL 2487/4885 |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | KRT18, LPO, KRTCAP2 | TSHR 4386/4885ALDH1A1 354/4885RECQL 3861/4885 |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | TSHR 4836/4885ALDH1A1 40/4885RECQL 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.