SCHEMBL1189097

SCHEMBL1189097

CC(C)(C)c1cc(C(=O)CBr)cc(C(C)(C)C)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
PTGS1 P23219 2/20 0.55
PTGS2 P35354 2/20 0.55
LMNA P02545 1/20 0.54
RECQL P46063 1/20 0.54
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
CA2 P00918 2/20 0.48
CA1 P00915 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
POLB P06746 1/20 0.47
TYR P14679 1/20 0.47
GAA P10253 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631723 0.90 CYP1A2 (0.50) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL12187574 0.90 ALOX5 (0.47) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL27532704 0.88 ALOX5 (0.46) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL1926015 0.85 ALOX5 (0.60) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL10268453 0.84 ALOX5 (0.43) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL2481961 0.84 LMNA (0.42) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL2345854 0.83 CA1 (0.53) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL1728964 0.83 LMNA (0.43) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL1928189 0.82 LMNA (0.61) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL7352493 0.81 PTGS2 (0.64) ALOX5PTGS1PTGS2LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772956-A Cleaning agent for dirt on outer surface of car body and preparation method thereof 广州市优贝材料科技有限公司 2024-10-15 CN claimed
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN claimed
CN-121519224-A Functional polyimide yarn and preparation method thereof 江苏集萃先进纤维材料研究所有限公司 2026-02-13 CN disclosed
CN-121473028-A Plant-based antibacterial fiber and preparation method thereof 南通博泉纺织品有限公司 2026-02-06 CN disclosed
CN-121161440-A Skin-friendly fabric for infants and preparation method thereof 南通博泉纺织品有限公司 2025-12-19 CN disclosed
CN-120502243-A Preparation method and application of photo-thermal dual-response film material 山西大学 2025-08-19 CN disclosed
CN-118772956-A Cleaning agent for dirt on outer surface of car body and preparation method thereof 广州市优贝材料科技有限公司 2024-10-15 CN disclosed
CN-118772956-A Cleaning agent for dirt on outer surface of car body and preparation method thereof 广州市优贝材料科技有限公司 2024-10-15 CN disclosed
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN disclosed
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN disclosed
EP-1675836-B1 DERIVATIVES OF 4-PHENYLTHIAZOLES AND THE USE THEREOF AS MEDICAMENTS FOR TREATING NEURODEGENERATIVE DISEASES, PAIN AND EPILEPSY IPSEN PHARMA (FR) 2016-04-13 EP disclosed
EP-0432740-A2 2-Substituted 4-(3-alkyl-5-tert.-butyl-4-hydroxy-phenyl)-thiazole, process for their preparation, medicaments containing them and their utilization HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-19 EP disclosed
US-4940790-A ANTIINFLAMMATORY AGENTS FOR RHEUMATIC DIORDERS AND PAIN HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
US-4908364-A Pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-13 US disclosed
US-4891374-A INFLAMMATORY RHEUMATIC DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 US disclosed
US-4636516-A ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIRHEUMATIC, ANTIPYRETIC, ANALGESIC YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-01-13 US disclosed
EP-0059090-B1 3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-01-29 EP disclosed
EP-0164765-A1 3,5-Di-Tert-Butyl-4-hydroxyphenyl-substituted heterocyclic compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1985-12-18 EP disclosed
US-4535165-A ANTIINFLAMMATORY, ANTIPYRETIC AGENTS, ANALGESICS, OXIDATION STABILIZERS OR ANTIBODY INHIBITORS RIKER LABORATORIES, INC. (US) 1985-08-13 US disclosed
EP-0059090-A1 3,5-Di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1982-09-01 EP disclosed