SCHEMBL1728964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9907147	0.86	TSHR (0.49)	LMNATSHRMEN1KMT2AALDH1A1
	SCHEMBL1730863	0.84	LMNA (0.46)	LMNARECQLPTGS1PTGS2ALOX5
	SCHEMBL1730641	0.83	NCOA1 (0.49)	LMNATSHRMEN1KMT2AMAPK1
	SCHEMBL1189097	0.83	ALOX5 (0.55)	LMNARECQLPTGS1PTGS2ALOX5
	SCHEMBL6544967	0.78	THRA (0.35)	LMNARECQLTSHRMAPK1KDM4E
	SCHEMBL1730615	0.77	MEN1 (0.38)	LMNATSHRMEN1KMT2AHTT
	SCHEMBL12187574	0.77	ALOX5 (0.47)	LMNARECQLPTGS1PTGS2ALOX5
	SCHEMBL9631723	0.77	CYP1A2 (0.50)	LMNARECQLPTGS1PTGS2ALOX5
	SCHEMBL27532704	0.76	ALOX5 (0.46)	LMNARECQLPTGS1PTGS2ALOX5
	SCHEMBL7859993	0.73	TSHR (0.46)	LMNATSHRMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.