SCHEMBL118930

SCHEMBL118930

NC(=O)OC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
F2 P00734 1/20 0.58
TSHR P16473 4/20 0.54
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
CYP3A4 P08684 1/20 0.54
PARP1 P09874 1/20 0.54
CYP2C19 P33261 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ALDH1A1 P00352 4/20 0.52
KMT2A Q03164 3/20 0.52
PARP10 Q53GL7 1/20 0.52
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28096283 1.00 LMNA (0.58) LMNAF2TSHRMAPTTDP1
Water SCHEMBL27554784 0.98 LMNA (0.56) LMNAF2TSHRMAPTTDP1
SCHEMBL27391027 0.98 LMNA (0.56) LMNAF2TSHRMAPTTDP1
SCHEMBL27844849 0.98 LMNA (0.56) LMNAF2TSHRMAPTTDP1
Ammonia Solution, Strong SCHEMBL27504543 0.98 F2 (0.56) LMNAF2TSHRMAPTTDP1
Phosphoric Acid SCHEMBL27779404 0.92 ALDH1A1 (0.50) LMNAF2TSHRMAPTTDP1
Bromobenzene SCHEMBL27920419 0.90 MAPT (0.56) LMNAF2TSHRMAPTTDP1
SCHEMBL27800215 0.88 TSHR (0.53) LMNAF2TSHRMAPTTDP1
Carbamic Acid SCHEMBL27556489 0.88 LMNA (0.61) LMNAF2TSHRMAPTTDP1
SCHEMBL30849215 0.87 PARP10 (0.42) LMNAF2MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117741125-A Bioconjugates having light-generated acidic or basic releasable detection moieties on biological tissues 美天施生物科技有限两合公司 2024-03-22 CN claimed
CN-115605461-A Fungicidal mixtures containing pyrazole derivatives FMC公司(US) 2023-01-13 CN claimed
EP-3551634-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
CN-109180543-A The preparation method of pesticide intermediate containing halogenated phenyl ring bisamide side-chain structure 绍兴贝斯美化工股份有限公司 2019-01-11 CN claimed
WO-2018108231-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
CN-107921172-A hemostatic compositions and devices 马克西姆·卡尔波夫 2018-04-17 CN claimed
CN-105294489-B 4 carbamoyl benzoate Buddha's warrior attendant alkyl ester contracting o-bromoaniline Schiff base nickel complexes synthesize and application 桂林理工大学 2017-12-12 CN claimed
CN-105153000-B The benzophenanthrene Anion Recognition acceptor of the thiocarbamide schiff bases side chain of sulfo-amino containing contracting and its application 桂林理工大学 2017-10-13 CN claimed
EP-1723952-A1 ANTIWRINKLING PREPARATION R & R Inc. (JP) 2006-11-22 EP claimed
EP-1572966-A3 COMPLETE BIOSYNTHETIC GENE SET FOR SYNTHESIS OF POLYKETIDE ANTIBIOTICS, INCLUDING THE ALBICIDIN FAMILY, RESISTANCE GENES AND USES THEREOF University of Florida (US) 2005-09-29 EP claimed
US-20050202055-A1 Anti-wrinkle agent KOICHI SHUDO, TOKYO, JAPAN 2005-09-15 US claimed
EP-1572966-A2 COMPLETE BIOSYNTHETIC GENE SET FOR SYNTHESIS OF POLYKETIDE ANTIBIOTICS, INCLUDING THE ALBICIDIN FAMILY, RESISTANCE GENES AND USES THEREOF University of Florida (US) 2005-09-14 EP claimed
WO-2004035760-A2 COMPLETE BIOSYNTHETIC GENE SET FOR BIOSYNTHESIS OF ALBICIDIN, RESISTANCE GENES, AND USES THEREOF UNIVERSITY OF FLORIDA (US) 2004-04-29 WO claimed
US-5936098-A Process for producing indoline compounds and intermediates for the production of the same TOKYO TANABE COMPANY LIMITED (JP) 1999-08-10 US claimed
CN-1069967-A Compound and fuel composition EXXON CHEMICAL PATENTS INC (US) 1993-03-17 CN claimed
CN-1063818-A IMPROVED ANTIPERSPIRANT FORMULATIONS STEPAN CO (US) 1992-08-26 CN claimed
US-4709016-A Molecular analytical release tags and their use in chemical analysis NORTHEASTERN UNIVERSITY (US) 1987-11-24 US claimed
US-4650750-A Method of chemical analysis employing molecular release tag compounds GIESE ROGER W (US) 1987-03-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050202055-A1 Anti-wrinkle agent RARA, RXRA, PPARA LMNA 64/4885F2 2579/4885TSHR 1880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.