Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | GRN | P28799 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23004918 | 1.00 | LTA4H (0.55) | LTA4HNPC1RAB9AMMEACE | |
| SCHEMBL11896295 | 1.00 | LTA4H (0.55) | LTA4HNPC1RAB9AMMEACE | |
| SCHEMBL19974930 | 0.95 | LTA4H (0.50) | LTA4HNPC1RAB9AMMEACE | |
| SCHEMBL23022995 | 0.89 | MMP1 (0.56) | LTA4HNPC1RAB9AMMEACE | |
| Hydrochloric Acid SCHEMBL23005018 | 0.87 | MMP1 (0.55) | LTA4HNPC1RAB9AMMEACE | |
| SCHEMBL23023028 | 0.86 | KLKB1 (0.51) | LTA4HNPC1RAB9AMMP1FCER2 | |
| SCHEMBL3794340 | 0.86 | KLKB1 (0.51) | LTA4HNPC1RAB9AMMP1FCER2 | |
| Hydrochloric Acid SCHEMBL23004846 | 0.85 | KLKB1 (0.50) | LTA4HNPC1RAB9AMMP1FCER2 | |
| SCHEMBL12861564 | 0.85 | ALDH1A1 (0.42) | LTA4HNPC1RAB9AMMEACE | |
| SCHEMBL30259421 | 0.84 | REN (0.50) | LTA4HNPC1RAB9AACEMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765763-B2 | Substituted piperazines as CGRP antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20120196872-A1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196872-A1 | NEW 5-ALKYNYL-PYRIDINES | CALCR, CALCRL, P2RX5 | LTA4H 527/4885NPC1 2460/4885RAB9A 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.