SCHEMBL11900526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1548021	0.87	HTT (0.51)	DGAT1ALDH1A1RAB9AKMT2AMAPT
	SCHEMBL1145090	0.86	ALDH1A1 (0.44)	DGAT1ALDH1A1HPGDALOX15TSHR
	SCHEMBL153069	0.86	DGAT1 (0.59)	DGAT1ALDH1A1HPGDTSHRRAB9A
	SCHEMBL29688799	0.86	DGAT1 (0.59)	DGAT1ALDH1A1HPGDTSHRRAB9A
	SCHEMBL3054837	0.83	DGAT1 (0.56)	DGAT1ALDH1A1RECQLTDP1RAB9A
	SCHEMBL6944180	0.82	CES2 (0.57)	ALDH1A1HPGDALOX15TSHRRECQL
	SCHEMBL13451235	0.82	DGAT1 (0.47)	DGAT1ALDH1A1HPGDTSHRRAB9A
	SCHEMBL18367285	0.81	DGAT1 (0.50)	DGAT1ALDH1A1HPGDTSHRHSD17B10
	SCHEMBL2240875	0.81	HPGD (0.46)	ALDH1A1HPGDALOX15TSHRRECQL
	SCHEMBL20134974	0.81	MEN1 (0.49)	ALDH1A1HPGDALOX15TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.