SCHEMBL11908094

SCHEMBL11908094

CC=CC(=O)Oc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 1/20 0.41
CA2 P00918 2/20 0.40
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
MMP9 P14780 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
USP2 O75604 2/20 0.34
CA12 O43570 2/20 0.34
RECQL P46063 1/20 0.34
CA1 P00915 1/20 0.34
CA7 P43166 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17481246 0.81 TYMS (0.46) PIK3C3CA2MAOAMAOBNPC1
SCHEMBL4474802 0.80 CA12 (0.51) NPC1RAB9AALDH1A1TDP1MAPT
SCHEMBL12337780 0.80 ALOX15 (0.43) CA2MAOAMAOBALDH1A1ALOX15
SCHEMBL20345840 0.79 CA2 (0.33) PIK3C3CA2NPC1RAB9AALDH1A1
SCHEMBL20548714 0.78 CA2 (0.37) PIK3C3CA2NPC1RAB9AALDH1A1
SCHEMBL20345784 0.77 CA2 (0.33) PIK3C3CA2NPC1RAB9AALDH1A1
SCHEMBL3320871 0.77 ALOX15 (0.40) CA2MAOAMAOBALDH1A1ALOX15
SCHEMBL19996956 0.76 ELANE (0.49) CA2NPC1ALDH1A1MAPTSMN1; SMN2
SCHEMBL20577752 0.76 CA2 (0.51) CA2MAOBALDH1A1TDP1MAPT
SCHEMBL20346205 0.76 CA2 (0.33) PIK3C3CA2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
EP-3259323-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-02-26 EP disclosed
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-01-30 US disclosed
US-10479848-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-19 US disclosed
US-10471398-B2 Graft copolymer functionalized article 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-12 US disclosed
US-10370322-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-06 US disclosed
EP-3502092-A1 ADDITION-FRAGMENTATION AGENTS 3M Innovative Properties Company (US) 2019-06-26 EP disclosed
US-10144760-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-04 US disclosed
WO-2014099317-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-26 WO disclosed
EP-2691772-A1 LIGAND FUNCTIONAL SUBSTRATES 3M Innovative Properties Company (US) 2014-02-05 EP disclosed
EP-2675783-A1 ADDITION-FRAGMENTATION AGENTS 3M Innovative Properties Company (US) 2013-12-25 EP disclosed
WO-2013184366-A1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-12 WO disclosed
WO-2013151739-A1 CROSSLINKABLE COMPOSITION COMPRISING PHOTOBASE GENERATORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-10-10 WO disclosed
WO-2013028401-A1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-28 WO disclosed
US-20120252091-A1 LIGAND FUNCTIONAL SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US disclosed
WO-2012134636-A1 LIGAND FUNCTIONAL SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-10-04 WO disclosed
WO-2012112304-A1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-23 WO disclosed
US-20120208965-A1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2012-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479848-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS PIK3C3 2415/4885CA2 3834/4885MAOA 1630/4885
US-10144760-B2 Ligand functional substrates PCNA, POLM, POLL PIK3C3 859/4885CA2 4376/4885MAOA 3550/4885
US-10370322-B2 Addition-fragmentation agents NR4A1, PARP14, MTX1 PIK3C3 4732/4885CA2 3487/4885MAOA 1964/4885
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS PIK3C3 2415/4885CA2 3834/4885MAOA 1630/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS PIK3C3 2415/4885CA2 3834/4885MAOA 1630/4885
US-20120252091-A1 LIGAND FUNCTIONAL SUBSTRATES PCNA, POLM, POLL PIK3C3 859/4885CA2 4376/4885MAOA 3550/4885
US-20120208965-A1 ADDITION-FRAGMENTATION AGENTS NR4A1, PARP14, MTX1 PIK3C3 4732/4885CA2 3487/4885MAOA 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.